Identifying Cell Cycle Modulators That Selectively Target ARID1A Deficiency Using High-Throughput Image-Based Screening

ARID1A, a component of the chromatin remodeling complex SWI/SNF, is an evolutionarily conserved complex that uses the energy of adenosine triphosphate hydrolysis to remodel chromatin structure and functions as a master regulator of gene transcription. Recent genomic studies have revealed that ARID1A...

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Bibliografiske detaljer
Udgivet i:SLAS Discov
Main Authors: Zhang, Lihong, Shen, Jianfeng, Yin, Yuping, Peng, Yang, Wang, Lulu, Hsieh, Hui-Ju, Shen, Qian, Brown, Powel H., Tao, Kaixiong, Uray, Ivan P., Peng, Guang
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921049/
https://ncbi.nlm.nih.gov/pubmed/28297605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217698942
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