Frequent Amplification of the Cyclin E Gene in Human Gastric Carcinomas

We searched for genetic alterations of the cyclin D1 and cyclin E genes in 45 human gastric carcinoma tissues. Expression of cyclin E mRNA and protein was also analyzed in eight of them by Northern and Western blots and immunohistochemical staining. The cyclin E gene was amplified 3–10 fold in seven...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Akama, Yoshihiko, Yasui, Wataru, Yokozaki, Hiroshi, Kuniyasu, Hiroki, Kitahara, Kenji, Ishikawa, Takenori, Tahara, Eiichi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1995
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920896/
https://ncbi.nlm.nih.gov/pubmed/7559076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb02442.x
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