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The expanding repertoire of targets for immune checkpoint inhibition in bladder cancer: What lies beneath the tip of the iceberg, PD-L1

Over the last decade, a new understanding of tumor-immune system interplay has been ushered in, lead in large part by the discovery of immune checkpoints mediated through B7-CD28 family interactions. Therapeutic blockade of the PD-L1 immune checkpoint pathway has already shown great success as a can...

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Podrobná bibliografie
Vydáno v:Urol Oncol
Hlavní autoři: Sankin, Alexander, Narasimhulu, Deepa, John, Peter, Gartrell, Benjamin, Schoenberg, Mark, Zang, Xingxing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920779/
https://ncbi.nlm.nih.gov/pubmed/28495553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urolonc.2017.04.007
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