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Opposing Kinesin and Myosin-I Motors Drive Membrane Deformation and Tubulation along Engineered Cytoskeletal Networks

Microtubule and actin filament molecular motors such as kinesin-1 and myosin-Ic (Myo1c) transport and remodel membrane-bound vesicles; however, it is unclear how they coordinate to accomplish these tasks. We introduced kinesin-1- and Myo1c-bound giant unilamellar vesicles (GUVs) into a micropatterne...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: McIntosh, Betsy B., Pyrpassopoulos, Serapion, Holzbaur, Erika L.F., Ostap, E. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920771/
https://ncbi.nlm.nih.gov/pubmed/29337076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.12.007
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