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Deletion of BMAL1 in Smooth Muscle Cells Protects Mice from Abdominal Aortic Aneurysms

OBJECTIVE: Abdominal aortic aneurysm (AAA) has high mortality rate when ruptured, but currently there is no proven pharmacological therapy for AAA due to our poor understanding of its pathogenesis. The current study explored a novel role of smooth muscle cell Arnt-like protein-1 (BMAL1), a transcrip...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Lutshumba, Jenny, Liu, Shu, Zhong, Yu, Hou, Tianfei, Daugherty, Alan, Lu, Hong, Guo, Zhenheng, Gong, Ming C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920729/
https://ncbi.nlm.nih.gov/pubmed/29437576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310153
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