Deficiency of Dab2 in myeloid cells exacerbates inflammation in liver and atherosclerotic plaques in LDL-R null mice

OBJECTIVE: Inflammatory macrophages promote the development of atherosclerosis. We have identified the adaptor protein disabled homolog 2 (Dab2) as a regulator of phenotypic polarization in macrophages. The absence of Dab2 in myeloid cells promotes an inflammatory phenotype but the impact of myeloid...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Arterioscler Thromb Vasc Biol
Päätekijät: Adamson, Samantha E., Polanowska-Grabowska, Renata, Marqueen, Kathryn, Griffiths, Rachael, Angdisen, Jerry, Breevoort, Sarah R., Schulman, Ira G., Leitinger, Norbert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920703/
https://ncbi.nlm.nih.gov/pubmed/29599136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310467
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