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2-Methoxypyridine as Thymidine Mimic in Watson-Crick Base Pairs of DNA and PNA: Synthesis, Thermal Stability and NMR Structural Studies

Development of nucleic acid base pair analogues that use new modes of molecular recognition is important for fundamental research and practical applications. The goal of this study was to evaluate 2-methoxypyridine as a cationic thymidine mimic in the A-T base pair. The hypothesis was that including...

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Foilsithe in:Chembiochem
Main Authors: Novosjolova, Irina, Kennedy, Scott D., Rozners, Eriks
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920655/
https://ncbi.nlm.nih.gov/pubmed/28858428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700400
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