Epigenetic Modifications in Thyroid Cancer Cells Restore NIS and Radio-Iodine Uptake and Promote Cell Death

Epigenetic modifications have been identified as being responsible for the de-differentiation of thyroid tissue and its malignant transformation. Cell proliferation inhibitory effects of the pan-deacetylase inhibitors panobinostat, SAHA and Trichostatin A (TSA), the modulation of the sodium iodide s...

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Pubblicato in:J Clin Med
Autori principali: Wächter, Sabine, Damanakis, Alexander I., Elxnat, Moritz, Roth, Silvia, Wunderlich, Annette, Verburg, Frederik A., Fellinger, Sebastian A., Bartsch, Detlef K., Di Fazio, Pietro
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920435/
https://ncbi.nlm.nih.gov/pubmed/29561759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm7040061
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