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Ginkgolic acids induce HepG2 cell death via a combination of apoptosis, autophagy and the mitochondrial pathway

Ginkgolic acids may induce malignant cell death via the B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax)/Bcl-2 apoptosis pathway. Concurrently, apoptosis, autophagy and mitochondrial dysfunction may also be involved in bringing about this endpoint. The anticancer effect of Ginkgolic acids (GAs)...

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Publicat a:Oncol Lett
Autors principals: Qi, Qian-Ming, Xue, Yin-Cun, Lv, Jian, Sun, Di, Du, Jian-Xin, Cai, Sheng-Qiang, Li, Yun-He, Gu, Tian-Cun, Wang, Mu-Bing
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920365/
https://ncbi.nlm.nih.gov/pubmed/29725398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8177
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