Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos

Triphenyl phosphate (TPHP) is an unsubstituted aryl phosphate ester used as a flame retardant and plasticizer within the United States. Using zebrafish as a model, the objectives of this study were to rely on (1) mRNA-sequencing to uncover pathways disrupted following embryonic TPHP exposure and (2)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Toxicol Sci
Main Authors: Mitchell, Constance A, Dasgupta, Subham, Zhang, Sharon, Stapleton, Heather M, Volz, David C
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Triphenyl Phosphate Cardiotoxicity in Zebrafish
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920347/
https://ncbi.nlm.nih.gov/pubmed/29529285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy037
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