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Regulation of Intracellular Triiodothyronine Is Essential for Optimal Macrophage Function

Innate immune cells, including macrophages, have recently been identified as target cells for thyroid hormone. We hypothesized that optimal intracellular concentrations of the active thyroid hormone triiodothyronine (T3) are essential for proinflammatory macrophage function. T3 is generated intracel...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: van der Spek, Anne H, Surovtseva, Olga V, Jim, Kin Ki, van Oudenaren, Adri, Brouwer, Matthijs C, Vandenbroucke-Grauls, Christina M J E, Leenen, Pieter J M, van de Beek, Diederik, Hernandez, Arturo, Fliers, Eric, Boelen, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920313/
https://ncbi.nlm.nih.gov/pubmed/29648626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00053
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