E2/E6 ratio and L1 immunoreactivity as biomarkers to determine HPV16-positive high-grade squamous intraepithelial lesions (CIN2 and 3) and cervical squamous cell carcinoma

OBJECTIVE: Human papillomavirus (HPV) 16 is the most carcinogenic HPV genotype. We investigated if HPV16 L1 capsid protein and E2/E6 ratio, evaluated by cervical cytology, may be used as biomarkers of ≥cervical intraepithelial neoplasia (CIN) 2 lesions. METHODS: Cervical specimens were obtained from...

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Detalhes bibliográficos
Publicado no:J Gynecol Oncol
Main Authors: Choi, Youn-Jin, Lee, Ahwon, Kim, Tae-Jung, Jin, Hyun-Tak, Seo, Yong-Bok, Park, Jong-Sup, Lee, Sung-Jong
Formato: Artigo
Idioma:Inglês
Publicado em: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920222/
https://ncbi.nlm.nih.gov/pubmed/29400024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3802/jgo.2018.29.e38
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