Screening for Lynch syndrome using risk assessment criteria in patients with ovarian cancer

OBJECTIVE: Lynch syndrome is a cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes. Lynch syndrome only causes about 0.4% of cases of ovarian cancer, which suggests that universal screening may not be cost-efficient. However, the frequency of Lynch syndrome...

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Detalhes bibliográficos
Publicado no:J Gynecol Oncol
Main Authors: Takeda, Takashi, Tsuji, Kosuke, Banno, Kouji, Yanokura, Megumi, Kobayashi, Yusuke, Tominaga, Eiichiro, Aoki, Daisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920216/
https://ncbi.nlm.nih.gov/pubmed/29400022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3802/jgo.2018.29.e29
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