Internalization of CD239 highly expressed in breast cancer cells: a potential antigen for antibody-drug conjugates

Antibody–drug conjugates (ADCs) are attractive in cancer therapy because they can directly bind to cancer cells and provide anticancer activity. To kill cancer cells with ADCs, the target antigens are required not only to be highly and/or selectively expressed on cancer cells but also internalized b...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Kikkawa, Yamato, Enomoto-Okawa, Yurie, Fujiyama, Aiko, Fukuhara, Takeshi, Harashima, Nozomi, Sugawara, Yumika, Negishi, Yoichi, Katagiri, Fumihiko, Hozumi, Kentaro, Nomizu, Motoyoshi, Ito, Yuji
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919910/
https://ncbi.nlm.nih.gov/pubmed/29700410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24961-4
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