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Accumulation of follicular CD8(+) T cells in pathogenic SIV infection

LN follicles constitute major reservoir sites for HIV/SIV persistence. Cure strategies could benefit from the characterization of CD8(+) T cells able to access and eliminate HIV-infected cells from these areas. In this study, we provide a comprehensive analysis of the phenotype, frequency, localizat...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Ferrando-Martinez, Sara, Moysi, Eirini, Pegu, Amarendra, Andrews, Sarah, Nganou Makamdop, Krystelle, Ambrozak, David, McDermott, Adrian B., Palesch, David, Paiardini, Mirko, Pavlakis, George N., Brenchley, Jason M., Douek, Daniel, Mascola, John R., Petrovas, Constantinos, Koup, Richard A.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919804/
https://ncbi.nlm.nih.gov/pubmed/29664020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96207
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