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Dunce Phosphodiesterase Acts as a Checkpoint for Drosophila Long-Term Memory in a Pair of Serotonergic Neurons

A key function of the brain is to filter essential information and store it in the form of stable, long-term memory (LTM). We demonstrate here that the Dunce (Dnc) phosphodiesterase, an important enzyme that degrades cAMP, acts as a molecular switch that controls LTM formation in Drosophila. We show...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Scheunemann, Lisa, Plaçais, Pierre-Yves, Dromard, Yann, Schwärzel, Martin, Preat, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919781/
https://ncbi.nlm.nih.gov/pubmed/29673482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.03.032
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