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A 12.3-kb Duplication Within the VWF Gene in Pigs Affected by Von Willebrand Disease Type 3

Von Willebrand Disease (VWD) type 3 is a serious and sometimes fatal hereditary bleeding disorder. In pigs, the disease has been known for decades, and affected animals are used as models for the human disease. Due to the recessive mode of inheritance of VWD type 3, severe bleeding is typically seen...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Lehner, Stefanie, Ekhlasi-Hundrieser, Mahnaz, Detering, Carsten, Allerkamp, Hanna, Pfarrer, Christiane, von Depka Prondzinski, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919753/
https://ncbi.nlm.nih.gov/pubmed/29208651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300432
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