p53 Gene Mutation in Hepatocellular Carcinoma Induced by 2‐Amino‐3‐methylimidazo[4,5‐f]quinoline in Nonhuman Primates

2‐Amino‐3‐methylimidazo[4,5‐f]quinoline (IQ) is one of several heterocyclic amines formed during the cooking of proteinaceous foods. IQ is a potent carcinogen in rodent bioassays and causes a high incidence of hepatocellular carcinomas in nonhnman primates. We examined 20 hepatocellular carcinomas (...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Fujimoto, Yoshinori, Hampton, Lori L., Snyderwine, Elizabeth G., Nagao, Minako, Sugimura, Takashi, Adamson, Richard H., Thorgeirsson, Snorri S.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1994
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919498/
https://ncbi.nlm.nih.gov/pubmed/8014109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02387.x
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