Brefeldin A Blocks the Cytotoxicity of T Cell Receptor α/β and γ/δ Cytotoxic T Lymphocyte Clones Reacting against Human Autologous Cancer Cells

We studied the effector mechanism of T cell receptor (TCR) α/β‐ and γ/δ‐type cytotoxic T lymphocyte (CTL) clones that react with human autologous tumor cells. Treatment of tumor cells with a fungal antibacterial reagent, brefeldin A (BFA), resulted in the inhibition of cytotoxicity of an autologous...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Wada, Yoshimasa, Ikeda, Hideyuki, Ueda, Daisuke, Ohta, Masahiko, Takahashi, Shuji, Hirata, Koichi, Sato, Noriyuki, Kikuchi, Kokichi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1993
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919263/
https://ncbi.nlm.nih.gov/pubmed/8407555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb02065.x
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