Glia-specific enhancers and chromatin structure regulate NFIA expression and glioma tumorigenesis

Long-range enhancer interactions critically regulate gene expression, yet little is known about how their coordinated activities contribute to CNS development, or how this may in turn relate to disease states. By examining the regulation of the transcription factor NFIA in the developing spinal cord...

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Vydáno v:Nat Neurosci
Hlavní autoři: Glasgow, Stacey M, Carlson, Jeffrey, Zhu, Wenyi, Chaboub, Lesley S, Kang, Peng, Lee, Hyun Kyoung, Clovis, Yoanne, Lozzi, Brittney, McEvilly, Robert J, Rosenfeld, Michael G, Creighton, Chad, Lee, Soo-Kyung, Mohila, Carrie, Deneen, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919190/
https://ncbi.nlm.nih.gov/pubmed/28892058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4638
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