Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids

Early endoderm progenitors naturally possess robust propagating potential to develop a majority of meter-long gastrointestinal tracts and are therefore considered as a promising source for therapy. Here, we demonstrated the reproducible generation of human CDX2(+) posterior gut endoderm cells (PGECs...

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Pubblicato in:Stem Cell Reports
Autori principali: Zhang, Ran-Ran, Koido, Masaru, Tadokoro, Tomomi, Ouchi, Rie, Matsuno, Tatsuya, Ueno, Yasuharu, Sekine, Keisuke, Takebe, Takanori, Taniguchi, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919071/
https://ncbi.nlm.nih.gov/pubmed/29429958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.006
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