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Enhanced Antitumor Activity and Reduced Toxicity of 1,3‐Bis(2‐chloroethyl)‐1‐nitrosourea Administered in Lipid Microspheres to Tumor‐bearing Mice
Stable lipid microspheres (LM) and lipid nanospheres (LN) with average diameters of 200 nm and 50 nm, respectively, were used to encapsulate an lipophilic antitumor agent, 1,3‐bis(2‐chloroethyl)‐1‐nitrosourea (BCNU). LM and LN containing BCNU (lipo BCNU and s‐lipo BCNU, respectively) were prepared b...
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| Publicado no: | Jpn J Cancer Res |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5919066/ https://ncbi.nlm.nih.gov/pubmed/8226282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb02804.x |
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