Site-specific glycosaminoglycan content is better maintained in the pericellular matrix than the extracellular matrix in early post-traumatic osteoarthritis

INTRODUCTION: One of the characteristics of early osteoarthritis (OA) is the loss of fixed charged density (FCD) of glycosaminoglycans in the superficial zone of articular cartilage. However, possible local changes in the FCD content of the pericellular matrix (PCM) are not fully understood. Hence,...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Ojanen, Simo P., Finnilä, Mikko A. J., Reunamo, Aino E., Ronkainen, Ari P., Mikkonen, Santtu, Herzog, Walter, Saarakkala, Simo, Korhonen, Rami K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919041/
https://ncbi.nlm.nih.gov/pubmed/29694389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196203
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