Proline oxidase controls proline, glutamate, and glutamine cellular concentrations in a U87 glioblastoma cell line

L-Proline is a multifunctional amino acid that plays an essential role in primary metabolism and physiological functions. Proline is oxidized to glutamate in the mitochondria and the FAD-containing enzyme proline oxidase (PO) catalyzes the first step in L-proline degradation pathway. Alterations in...

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Udgivet i:PLoS One
Main Authors: Cappelletti, Pamela, Tallarita, Elena, Rabattoni, Valentina, Campomenosi, Paola, Sacchi, Silvia, Pollegioni, Loredano
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918996/
https://ncbi.nlm.nih.gov/pubmed/29694413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196283
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