Modifying Effects of Various Chemicals on Tumor Development in a Rat Wide‐spectrum Organ Carcinogenesis Model

The efficacy of a wide‐spectrum organ carcinogenesis model for detection of modification potential of exogenous agents was investigated in F344 male rats. Groups of animals were sequentially injected with N‐bis(2‐hydroxypropyl)nitrosamine (1000 mg/kg body weight, i.p., in saline, twice in week 1), N...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Uwagawa, Satoshi, Tsuda, Hiroyuki, Ozaki, Keisuke, Takahashi, Satoru, Yamaguchi, Shuji, Mutai, Mamoru, Aoki, Toyohiko, Ito, Nobuyuki
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1992
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918946/
https://ncbi.nlm.nih.gov/pubmed/1399818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb01985.x
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