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Oncolytic Viruses as Antigen Agnostic Tumor Vaccines
Selective destruction of neoplastic tissues by oncolytic viruses (OV) leads to antigen-agnostic boosting of neoantigen-specific cytotoxic T lymphocyte (CTL) responses, making OV ideal companions for checkpoint blockade therapy. Here we discuss the mechanisms whereby OV modulate both adjuvanticity an...
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| Publicado no: | Cancer Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5918693/ https://ncbi.nlm.nih.gov/pubmed/29634947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.011 |
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