Species Difference among Experimental Rodents in Induction of P450IA Family Enzymes by 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine

Rats, mice, hamsters and guinea pigs were given an i.p. injection of 2‐amino‐1‐methyl‐6‐phenyl‐imidazo[4,5‐b]pyridine (PhIP), a protein‐derived pyrolysate component present in cooked foods, and inductions of cytochrome P450 (P450) in the liver and kidney of these animals were examined. The activity...

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Pubblicato in:Jpn J Cancer Res
Autori principali: Degawa, Masakuni, Kobayashi, Ken‐ichiro, Miura, Shin‐ichi, Arai, Hiroshi, Esumi, Hiroyasu, Sugimura, Takashi, Hashimoto, Yoshiyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1992
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918673/
https://ncbi.nlm.nih.gov/pubmed/1452456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb02720.x
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