Cytotoxic Effects of Vitamin A in Combination with Vincristine, Daunorubicin and 6‐Thioguanine upon Cells from Lymphoblastic Leukemic Patients

We studied whether isotretinoin potentiated the effects of vincristine (VCR), daunorubicin (DNR), and 6‐thioguanine (6‐TG) against cells obtained from 24 patients with acute lymphoblastic leukemia (ALL). Treatment with 5 μg/ml isotretinoin alone resulted in a leukemic cell survival of 82%± 28.1%. So...

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Dettagli Bibliografici
Pubblicato in:Jpn J Cancer Res
Autori principali: Pieters, Rob, Huismans, Dieuwke R., Loonen, Anne H., Hählen, Karel, Veerman, Anjo J. P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1991
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918603/
https://ncbi.nlm.nih.gov/pubmed/1938600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01942.x
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