Sequence‐dependent Termination of Mammalian DNA Polymerase Reaction by a New Platinum Compound, (–)‐(R)‐2‐Aminomethylpyrrolidine(1,1‐cyclobutane‐dicarboxylato)‐2‐platinum(II) Monohydrate

We examined the mechanisms of the inhibition of DNA synthesis by a new platinum compound, (‐)‐(R)‐2‐aminomethylpyrrolidine(1,1‐cyclobutane‐dicarboxylato)‐2‐platinum(II) monohydrate (DWA‐2114R), a derivative of the antitumor drug cis‐ diamminedichloroplatinum(II) (CDDP), using prokaryotic and eukaryo...

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Publicado en:Jpn J Cancer Res
Autores principales: Iwata, Mitsumasa, Izuta, Shunji, Suzuki, Motoshi, Kojima, Kiyohide, Furuhashi, Yoshihito, Tomoda, Yutaka, Yoshida, Shonen
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 1991
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918450/
https://ncbi.nlm.nih.gov/pubmed/1904423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01867.x
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