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Inhibitory Effect of 8‐Chloro‐cyclic Adenosine 3′,5′‐Monophosphate on Cell Growth of Gastric Carcinoma Cell Lines

A cAMP analogue, 8‐chloro‐cAMP (8‐Cl‐cAMP), selectively binds to site 1 receptor of type II regulatory subunit (RII) of cAMP‐dependent protein kinase. The effects of 8‐Cl‐cAMP on human gastric carcinoma cell lines were studied. Twenty μM 8‐CI‐cAMP clearly inhibited cell growth in six cell lines (TMK...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Takanashi, Atsushi, Yasui, Wataru, Yoshida, Kazuhiro, Yokozaki, Hiroshi, Saito, Daizo, Abe, Kaoru, Urakami, Kenichi, Mild, Keizaburo, Tahara, Eiichi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918396/
https://ncbi.nlm.nih.gov/pubmed/1850725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01849.x
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