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Rapid Induction of Endometrial Carcinoma in ICR Mice Treated with N‐Methyl‐N‐nitrosourea and 17β‐Estradiol

The present study was undertaken to develop an animal model for endometrial neoplasms. A total of 107 female ICR mice, 10 weeks of age, were used and treated as follows: Group 1 (31 mice) was given intravaginal instillation of N‐methyl‐N‐nitrosourea (MNU) solution (1 mg/100 g body wt.) once a week f...

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Publicado en:Jpn J Cancer Res
Autores principales: Niwa, Kenji, Tanaka, Takuji, Mori, Hideki, Yokoyama, Yasuhiro, Furui, Tatsuro, Mori, Hidehiro, Teruhiko, Teruhiko
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 1991
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918362/
https://ncbi.nlm.nih.gov/pubmed/1778763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01811.x
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