Synergistic Enhancement of Glutathione S–Transferase Placental Form–positive Hepatic Foci Development in Diethylnitrosamine–treated Rats by Combined Administration of Five Heterocyclic Amines at Low Doses

Potential synergism among 5 heterocyclic amines at low doses in the induction of glutathione S–transferase placental form (GST–P)–positive liver cell foci was examined in an 8–week experiment using male rats initially given diethylnitrosamine (200 mg/kg, ip). The heterocyclic amines applied were 3–a...

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Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Hasegawa, Ryohei, Shirai, Tomoyuki, Hakoi, Kazuo, Takaba, Katsumi, Iwasaki, Shogo, Hoshiya, Toru, Ito, Nobuyuki, Nagao, Minako, Takashi, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 1991
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918350/
https://ncbi.nlm.nih.gov/pubmed/1778761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01809.x
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