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Induction of Renal Cell Tumors in Rats and Mice, and Enhancement of Hepatocellular Tumor Development in Mice after Long‐term Hydroquinone Treatment

Hydroquinone (HQ) was administered to F344 rats and B6C3F(1) mice of both sexes at a level of 0.8% in the diet for two years. This treatment induced renal tubular hyperplasia as well as adenomas, predominantly in males of both species, and was associated with chronic nephropathy in rats. In addition...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Shibata, Masa‐Aki, Hirose, Masao, Tanaka, Hikaru, Asakawa, Emiko, Shirai, Tomoyuki, Ito, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918322/
https://ncbi.nlm.nih.gov/pubmed/1752780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01783.x
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