The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia

Bone marrow derived mesenchymal stromal cells (BM-MSCs) have been shown to have significant therapeutic effects in experimental models of pneumonia and lung injury. The current study examined the roles of the toll like receptor 4 (TLR4) and protease activated receptor 1 (PAR1) pathways on MSC surviv...

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Bibliografiske detaljer
Udgivet i:Stem Cells
Main Authors: Gupta, N, Sinha, R, Krasnodembskaya, A, Xu, X, Nizet, V, Matthay, MA, Griffin, JH
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918231/
https://ncbi.nlm.nih.gov/pubmed/29396891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2796
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