Overexpression of 11β-hydroxysteroid dehydrogenase 1 in visceral adipose tissue and underexpression of endothelial nitric oxide synthase in the adrenal cortex of dogs with hyperadrenocorticism

11β-Hydroxysteroid dehydrogenase 1 (11β-HSD1) is an enzyme that activates cortisone into cortisol in tissues. Alterations in this enzyme are related to the development of metabolic syndrome, obesity and hyperadrenocorticism (HAC). Endothelial nitric oxide synthase (eNOS) produces nitric oxide and is...

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Detalhes bibliográficos
Publicado no:Open Vet J
Main Authors: Miceli, Diego Daniel, Abiuso, Adriana María Belén, Vidal, Patricia Noemi, Gallelli, María Florencia, Pignataro, Omar Pedro, Castillo, Victor Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: Faculty of Veterinary Medicine, University of Tripoli and Libyan Authority for Research, Science and Technology 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918128/
https://ncbi.nlm.nih.gov/pubmed/29721436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4314/ovj.v8i1.13
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