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Overexpression of 11β-hydroxysteroid dehydrogenase 1 in visceral adipose tissue and underexpression of endothelial nitric oxide synthase in the adrenal cortex of dogs with hyperadrenocorticism

11β-Hydroxysteroid dehydrogenase 1 (11β-HSD1) is an enzyme that activates cortisone into cortisol in tissues. Alterations in this enzyme are related to the development of metabolic syndrome, obesity and hyperadrenocorticism (HAC). Endothelial nitric oxide synthase (eNOS) produces nitric oxide and is...

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Bibliografske podrobnosti
izdano v:Open Vet J
Main Authors: Miceli, Diego Daniel, Abiuso, Adriana María Belén, Vidal, Patricia Noemi, Gallelli, María Florencia, Pignataro, Omar Pedro, Castillo, Victor Alejandro
Format: Artigo
Jezik:Inglês
Izdano: Faculty of Veterinary Medicine, University of Tripoli and Libyan Authority for Research, Science and Technology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918128/
https://ncbi.nlm.nih.gov/pubmed/29721436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4314/ovj.v8i1.13
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