Increase in the Level of P‐Glycoprotein mRNA Expression in Multidrug‐resistant K562 Cell Lines Treated with Sodium Butyrate Is Not Accompanied with Erythroid Differentiation

We examined the effects of hemin, sodium butyrate and mitomycin C on levels of P‐glycoprotein mRNA in human myelogenous K562 cells by northern blot analysis. After treatment with sodium butyrate a dose‐dependent increase of P‐glycoprotein mRNA expression was observed in the adriamycin‐resistant K562...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Shibata, Hiroyuki, Kanamaru, Ryunosuke, Sato, Toshiaki, Ishioka, Chikashi, Konishi, Yukari, Ishikawa, Akira, Wakui, Akira, Tsuruo, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1990
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918010/
https://ncbi.nlm.nih.gov/pubmed/1980493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02681.x
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