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Association of Elevated Expression of the c‐erbB‐2 Protein with Spread of Breast Cancer

We analyzed amplification and expression of the c‐erbB‐2 gene in human breast cancers. Southern blot hybridization analysis demonstrated amplification of the c‐erbB‐2 gene in 10 out of 50 tumor DNAs examined. The degree of amplification was three‐ to twenty‐fold relative to normal placenta. The c‐er...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Yamada, Yukinori, Yoshimoto, Masataka, Murayama, Yoichi, Ebuchi, Masakazu, Mori, Shigeo, Yamamoto, Tadashi, Sugano, Haruo, Toyoshima, Kumao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917922/
https://ncbi.nlm.nih.gov/pubmed/2576425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb01654.x
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