Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells

Immune-aging is associated with perturbed immune responses in the elderly. CD161-expressing T cells, i.e., the previously described subsets of CD161(+) CD4(+) T cells, CD161(high) CD8(+) T cells, and CD161(int) CD8(+) T cells, are highly functional, pro-inflammatory T cells. These CD161-expressing T...

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Publicado en:Front Immunol
Autores principales: van der Geest, Kornelis S. M., Kroesen, Bart-Jan, Horst, Gerda, Abdulahad, Wayel H., Brouwer, Elisabeth, Boots, Annemieke M. H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917671/
https://ncbi.nlm.nih.gov/pubmed/29725326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00752
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