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Vincristine‐resistant Human Cancer KB Cell Line and Increased Expression of Multidrug‐resistance Gene
A multidrug‐resistant clone of human cancer KB cells was isolated by stepwise selection on exposure to increasing doses of vincristine. The final clone, VJ‐300, obtained after ethylmethane sulfonate mutagenesis showed 400‐fold higher resistance to vincristine than did KB cells. Cellular accumulation...
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| Publicado no: | Jpn J Cancer Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5917651/ https://ncbi.nlm.nih.gov/pubmed/2906349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1988.tb01550.x |
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