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Carcinogenesis by Nitrosohydroxyethylurea and Nitrosomethoxyethylurea in F344 Rats

Nitroso ‐ 2 ‐ hydroxyethylurea and its methyl ether, nitroso ‐ 2 ‐ methoxyethylurea, were administered to male and female rats by gavage, each at two dose rates. The highest dose rate of nitrosohydroxyethylurea was 14 mg twice a week for 18 weeks, which led to death of all animals by week 34 with a...

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Bibliographic Details
Published in:Jpn J Cancer Res
Main Authors: Lijinsky, William, Kovatch, Robert M.
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917469/
https://ncbi.nlm.nih.gov/pubmed/3130352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1988.tb01575.x
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