Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

Inflammatory bowel disease (IBD) is a chronic intestinal disorder, with two main types: Crohn’s disease (CD) and ulcerative colitis (UC), whose molecular pathology is not well understood. The majority of IBD-associated SNPs are located in non-coding regions and are hard to characterize since regulat...

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Publicat a:Nat Commun
Autors principals: Boyd, Mette, Thodberg, Malte, Vitezic, Morana, Bornholdt, Jette, Vitting-Seerup, Kristoffer, Chen, Yun, Coskun, Mehmet, Li, Yuan, Lo, Bobby Zhao Sheng, Klausen, Pia, Jan Schweiger, Pawel, Pedersen, Anders Gorm, Rapin, Nicolas, Skovgaard, Kerstin, Dahlgaard, Katja, Andersson, Robin, Terkelsen, Thilde Bagger, Lilje, Berit, Troelsen, Jesper Thorvald, Petersen, Andreas Munk, Jensen, Kim Bak, Gögenur, Ismail, Thielsen, Peter, Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Bjerrum, Jacob Tveiten, Sandelin, Albin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916929/
https://ncbi.nlm.nih.gov/pubmed/29695774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03766-z
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