Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

Inflammatory bowel disease (IBD) is a chronic intestinal disorder, with two main types: Crohn’s disease (CD) and ulcerative colitis (UC), whose molecular pathology is not well understood. The majority of IBD-associated SNPs are located in non-coding regions and are hard to characterize since regulat...

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Publicado no:Nat Commun
Main Authors: Boyd, Mette, Thodberg, Malte, Vitezic, Morana, Bornholdt, Jette, Vitting-Seerup, Kristoffer, Chen, Yun, Coskun, Mehmet, Li, Yuan, Lo, Bobby Zhao Sheng, Klausen, Pia, Jan Schweiger, Pawel, Pedersen, Anders Gorm, Rapin, Nicolas, Skovgaard, Kerstin, Dahlgaard, Katja, Andersson, Robin, Terkelsen, Thilde Bagger, Lilje, Berit, Troelsen, Jesper Thorvald, Petersen, Andreas Munk, Jensen, Kim Bak, Gögenur, Ismail, Thielsen, Peter, Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Bjerrum, Jacob Tveiten, Sandelin, Albin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916929/
https://ncbi.nlm.nih.gov/pubmed/29695774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03766-z
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