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Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis

Nonsyndromic craniosynostosis (NSC) is the most common craniosynostosis with the primary defect being one or more fused sutures. In contrast to syndromic craniosynostosis, the etiopathogenesis of NSC is largely unknown. Here we show that autophagy, a major catabolic process required for the maintena...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Qiu, Shanshan, Wang, Jing, Huang, Siqi, Sun, Shouqing, Zhang, Zhen, Bao, Nan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916928/
https://ncbi.nlm.nih.gov/pubmed/29695736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24885-z
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