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Uncovering inherent cellular plasticity of multiciliated ependyma leading to ventricular wall transformation and hydrocephalus

Specialized, differentiated cells often perform unique tasks that require them to maintain a stable phenotype. Multiciliated ependymal cells (ECs) are unique glial cells lining the brain ventricles, important for cerebral spinal fluid circulation. While functional ECs are needed to prevent hydroceph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Abdi, Khadar, Lai, Chun-Hsiang, Paez-Gonzalez, Patricia, Lay, Mark, Pyun, Joon, Kuo, Chay T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916891/
https://ncbi.nlm.nih.gov/pubmed/29695808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03812-w
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