Proliferation of endogenous regulatory T cells improve the pathophysiology associated with placental ischaemia of pregnancy

PROBLEM: Preeclampsia (PE) is associated with inflammation and decreased Treg cells and IL-10. The reduced uterine perfusion pressure (RUPP) rat model of PE exhibits these characteristics, and we hypothesized that induction of endogenous Tregs by a specific stimulus (CD28 superagonistic monoclonal a...

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Foilsithe in:Am J Reprod Immunol
Main Authors: Ibrahim, Tarek, Przybyl, Lukasz, Harmon, Ashlyn C., Amaral, Lorena M., Faulkner, Jessica L., Cornelius, Denise C., Cunningham, Mark W., Hünig, Thomas, Herse, Florian, Wallukat, Gerd, Dechend, Ralf, LaMarca, Babbette
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916789/
https://ncbi.nlm.nih.gov/pubmed/28681467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.12724
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