Controllable and uncontrollable stress differentially impact pathogenicity and survival in a mouse model of viral encephalitis

Intranasal instillation of vesicular stomatitis virus (VSV) into mice given controllable stress (modeled by escapable foot shock, ES) resulted in enhanced pathogenicity and decreased survival relative to infected mice given uncontrollable stress (modeled by inescapable foot shock, IS) and non-shocke...

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Udgivet i:J Neuroimmunol
Main Authors: Ciavarra, Richard P., Machida, Mayumi, Lundberg, Patric S., Gauronskas, Phillip, Wellman, Laurie L., Steel, Christina, Sanford, Larry D.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916739/
https://ncbi.nlm.nih.gov/pubmed/29580714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2018.02.014
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