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The PTENP1 Pseudogene, Unlike the PTEN Gene, Is Methylated in Normal Endometrium, As Well As in Endometrial Hyperplasias and Carcinomas in Middle-Aged and Elderly Females

The tumor suppressor PTEN controls multiple cellular functions, including cell cycle, apoptosis, senescence, transcription, and mRNA translation of numerous genes. In tumor cells, PTEN is frequently inactivated by genetic mutations and epimutations. The aim of this study was to investigate the methy...

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Detalhes bibliográficos
Publicado no:Acta Naturae
Main Authors: Kovalenko, T. F., Morozova, K. V., Ozolinya, L. A., Lapina, I. A., Patrushev, L. I.
Formato: Artigo
Idioma:Inglês
Publicado em: A.I. Gordeyev 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916733/
https://ncbi.nlm.nih.gov/pubmed/29713518
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