Soluble guanylyl cyclase is a critical regulator of migraine-associated pain

BACKGROUND: Nitric oxide (NO) has been heavily implicated in migraine. Nitroglycerin is a prototypic NO-donor, and triggers migraine in humans. However, nitroglycerin also induces oxidative/nitrosative stress and is a source of peroxynitrite - factors previously linked with migraine etiology. Solubl...

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Veröffentlicht in:Cephalalgia
Hauptverfasser: Ben Aissa, Manel, Tipton, Alycia F., Bertels, Zachariah, Gandhi, Ronak, Moye, Laura S., Novack, Madeline, Bennett, Brian M., Wang, Yueting, Litosh, Vladislav, Lee, Sue. H., Gaisina, Irina N., Thatcher, Gregory R. J., Pradhan, Amynah A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916516/
https://ncbi.nlm.nih.gov/pubmed/29022756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0333102417737778
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