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Subacute intranasal administration of tissue plasminogen activator improves stroke recovery by inducing axonal remodeling in mice
In addition to thrombolysis, tissue plasminogen activator (tPA) can evoke neurorestorative processes. We therefore investigated the therapeutic effect of subacute intranasal administration of tPA post stroke on neurological recovery and on corticospinal innervation in mice. A transgenic mouse line,...
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| Publicado no: | Exp Neurol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5916497/ https://ncbi.nlm.nih.gov/pubmed/29518364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.03.001 |
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