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Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice

Transcriptome-based drug discovery has identified new treatments for some complex diseases, but has not been applied to alcohol use disorder (AUD) or other psychiatric diseases, where there is a critical need for improved pharmacotherapies. High Drinking in the Dark (HDID-1) mice are a genetic model...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Ferguson, Laura B, Ozburn, Angela R, Ponomarev, Igor, Metten, Pamela, Reilly, Matthew, Crabbe, John C, Harris, R Adron, Mayfield, R Dayne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916369/
https://ncbi.nlm.nih.gov/pubmed/29251283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.301
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