Association of Serotonin Transporter Gene AluJb Methylation with Major Depression, Amygdala Responsiveness, 5-HTTLPR/rs25531 Polymorphism, and Stress

DNA methylation profiles of the serotonin transporter gene (SLC6A4) have been shown to alter SLC6A4 expression, drive antidepressant treatment response and modify brain functions. This study investigated whether methylation of an AluJb element in the SLC6A4 promotor was associated with major depress...

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Publicado en:Neuropsychopharmacology
Main Authors: Schneider, Ilona, Kugel, Harald, Redlich, Ronny, Grotegerd, Dominik, Bürger, Christian, Bürkner, Paul-Christian, Opel, Nils, Dohm, Katharina, Zaremba, Dario, Meinert, Susanne, Schröder, Nina, Straßburg, Anna Milena, Schwarte, Kathrin, Schettler, Christiane, Ambrée, Oliver, Rust, Stephan, Domschke, Katharina, Arolt, Volker, Heindel, Walter, Baune, Bernhard T, Zhang, Weiqi, Dannlowski, Udo, Hohoff, Christa
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2018
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916353/
https://ncbi.nlm.nih.gov/pubmed/29114103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.273
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